Figure 9

Transmission electron microscope images of ablated tumor tissue. (A) MR-guided HIFU alone. The blue arrows indicate the interrupted cell membranes. (B) MR-guided HIFU + pure PLGA microcapsules. The white arrows indicate the distended mitochondria. (C) MR-guided HIFU + PLGA-coated Fe₃O₄ microcapsules. The black arrows indicate the superparamagnetic PLGA-coated Fe₃O₄ microcapsules.