Figure 2From: MicroRNA-21 is a candidate driver gene for 17q23-25 amplification in ovarian clear cell carcinoma Analysis of clinical CCC specimens. Of the 9 tumors with 17q23-25 amplification, 7 (77.7%) showed miR-21 overexpression. Of the 19 tumors (58.8%) without 17q23-25 amplification, 10 showed miR-21 overexpression. Of all the 28 17q23-25 amplification cases, both miR-21 overexpression and PTEN protein loss were detected in 4 (14.2%).Back to article page