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Table 1 Characteristics of the six trials included in the meta-analysis

From: Prophylactic cranial irradiation for patients with small-cell lung cancer: a systematic review of the literature with meta-analysis

Author Year Age (Years) Median follow-up (month) Total dose/No. of fraction (Dose/Fraction) No. of patients
   PCI No PCI    
Gregor [11] 1997 60 (37–79) 61 (28–76) 18 36 Gy/18 (2 Gy) 314
24 Gy/12 (2 Gy)
Laplanche [13] 1998 58 57 - 24-30 Gy/8-10 211
Cao KJ [14] 2005 54.69 ± 7.56 55.63 ± 7.29 60 36-40 Gy/18-20 51
Slotman [15] 2007 63 (37–75) 63 (39–75) 9 20-30 Gy/5-12 286
Schild [8] 2012 63 (34–79) 63 (37–80) 72 30 Gy/15 (2 Gy) 739
25 Gy/10 (2.5 Gy)