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Figure 4 | BMC Cancer

Figure 4

From: Bmi1 regulates self-renewal and epithelial to mesenchymal transition in breast cancer cells through Nanog

Figure 4

Knockdown of Bmi1 increased sensitivity of cells to cytotoxic drug doxorubicin and reduced tumorigenicity. The graphs show the dose–response curve of NBLE-LP (A) and MDAMB231 (B) cells with vector alone control or shBmi1, treated with doxorubicin for 48 hrs (n =3). C. The chart shows number of tumors formed by MDAMB231 cells with vector alone control or with shBmi1.

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