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Table 2 Summary of the comparison of the diagnoses based on the biopsy, the endoscopy, the EUS, Paris classification, ER specimens with the gold standard

From: Diagnosis and staging of superficial esophageal precursor based on pre-endoscopic resection system comparable to endoscopic resection

 

Final Diagnosis

P value

 

Pathological diagnosis

Invasive depth

 
 

LGIN

MGIN

HGIN

ESCC

Mucosa

Submucosa

 

Biopsy diagnosis

<0.05

LGIN

0

4

5

3

NA

NA

 

MGIN

0

11

7

5

NA

NA

 

HGIN

0

0

94

57

NA

NA

 

ESCC

0

0

0

31

NA

NA

 

EUS

<0.05

Mucosa

NA

NA

NA

NA

143

11

 

Submucosa

NA

NA

NA

NA

46

17

 

Paris classification

<0.05

0-IIa

0

17

48

66

NA

NA

 

0-IIb

0

14

89

150

NA

NA

 

0-IIc

0

0

0

1

NA

NA

 

Noninvasive

0

13

91

52

NA

NA

 

Invasive

0

2

15

44

NA

NA

 

Endoscopic diagnosis

<0.05

LGIN

0

7

11

2

NA

NA

 

MGIN

0

3

27

6

NA

NA

 

HGIN

0

4

61

53

NA

NA

 

ESCC

0

1

7

35

NA

NA

 

ER diagnosis

<0.05

LGIN

0

5

7

1

NA

NA

 

MGIN

0

10

20

0

NA

NA

 

HGIN

0

2

77

3

NA

NA

 

ESCC

0

0

2

92

NA

NA

 

Pre-ER diagnosis

<0.05

LGIN

0

0

0

0

NA

NA

 

MGIN

0

9

6

0

NA

NA

 

HGIN

0

4

93

0

NA

NA

 

ESCC

0

2

7

96

NA

NA

 
  1. LGIN: low-grade intra-epithelia neoplasia; MGIN: middle-grade intra-epithelia neoplasia; HGIN: high-grade intra-epithelia neoplasia; ESCC: esophageal squmous cell carcinoma.