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Table 1 IC 50 values (nM) for paclitaxel, docetaxel, epirubicin, doxorubicin and carboplatin in isogenic MDA-MB-231 and ZR75-1 cell lines

From: Molecular characterisation of isogenic taxane resistant cell lines identify novel drivers of drug resistance

  Paclitaxel Docetaxel Epirubicin Doxorubicin Carboplatin
MDA-MB-231 1.6 0.8 35.15 35.64 208
MDA-MB-231 25PACR 29.61 6.4 34.25 61.38 212
MDA-MB-231 50PACR 89.98 10.16 30.39 30.12 266
ZR75-1 2.76 3.1 16.96 24.18 342.6
ZR75-1 25PACR 470.8 134.3 330.7 324.2 342.8
ZR75-1 50PACR 489.1 489.1 318.7 224.4 369.2
ZR75-1 25DOCR 41.24 42.13 3516 255.5 408.8
ZR75-1 50DOCR 310.1 47.24 506.9 676.7 386.9