Table 1 IC 50 values (nM) for paclitaxel, docetaxel, epirubicin, doxorubicin and carboplatin in isogenic MDA-MB-231 and ZR75-1 cell lines
Paclitaxel | Docetaxel | Epirubicin | Doxorubicin | Carboplatin | |
|---|---|---|---|---|---|
MDA-MB-231 | 1.6 | 0.8 | 35.15 | 35.64 | 208 |
MDA-MB-231 25PACR | 29.61 | 6.4 | 34.25 | 61.38 | 212 |
MDA-MB-231 50PACR | 89.98 | 10.16 | 30.39 | 30.12 | 266 |
ZR75-1 | 2.76 | 3.1 | 16.96 | 24.18 | 342.6 |
ZR75-1 25PACR | 470.8 | 134.3 | 330.7 | 324.2 | 342.8 |
ZR75-1 50PACR | 489.1 | 489.1 | 318.7 | 224.4 | 369.2 |
ZR75-1 25DOCR | 41.24 | 42.13 | 3516 | 255.5 | 408.8 |
ZR75-1 50DOCR | 310.1 | 47.24 | 506.9 | 676.7 | 386.9 |