Table 3 EORTC QLQ-C30 symptom domains and time point of questionnaire completion (54 patients, 561 QOL assessments)
EORTC QLQ-C30 | At the hospital | At home (1 week later) | At home (2 weeks later) | Time point (main effect) F/p values |
|---|---|---|---|---|
Estimated mean (95% CI) | ||||
Fatigue | 34.2 1w, 2w(29.2-39.3) | 43.3 Ho, 2w (38.2-48.3) | 39.8 Ho, 1w (34.4-45.1) | F = 21.40; p < 0.001 |
Nausea/Vomiting | 6.1 1w(3.3-8.9) | 12.7 Ho, 2w (9.8-15.5) | 8.3 1w(5.2-11.4) | F = 19.89; p < 0.001 |
Pain | 18.7(13.5-24.0) | 21.7(16.4-27.0) | 21.6(16.0-27.1) | F = 2.51; p = 0.083 |
Dyspnoea | 22.8 1w(16.1-29.5) | 26.3 Ho, 2w(19.6-33.1) | 22.9 1w(16.0-29.8) | F = 3.92; p = 0.021 |
Sleeping Disturbances | 26.0 1w(20.1-32.0) | 34.4 Ho, 2w (28.4-40.5) | 29.6 1w(23.3-36.0) | F = 12.37; p < 0.001 |
Appetite Loss | 12.8 1w(7.5-18.1) | 21.7 Ho, 2w (16.4-27.1) | 15.6 1w(9.9-21.3) | F = 14.94; p < 0.001 |
Constipation | 13.3 1w, 2w(8.1-18.5) | 23.1 Ho (17.8-28.4) | 19.4 Ho (13.7-25.2) | F = 13.70; p < 0.001 |
Diarrhoea | 7.1(4.1-10.2) | 7.3(4.2-10.3) | 6.0(2.6-9.3) | F = 0.46; p = 0.634 |
Financial Impact | 16.6(10.5-22.7) | 18.4(12.3-24.5) | 18.9 (12.6-25.1) | F = 2.94; p = 0.054 |