Tissue type
|
Number of tissues N
|
Nuclear Ep-ICD positivity n (%)
|
Cytoplasmic Ep-ICD positivity n (%)
|
Membranous EpEx positivity n (%)
|
Loss of membranous EpEx n (%)
|
---|
Normal
|
45
|
11 (24% )
|
39 (87%)
|
19 (42%)
|
26 (58%)
|
Breast cancer
|
266
|
121 (46%)
|
215 (81%)
|
185 (70%)
|
81 (30%)
|
Histotypes
*
| | | | | |
DCIS
|
61 (22.9%)
|
30 (49%)
|
48 (79%)
|
47 (77%)
|
14 (23%)
|
IDC
|
180 (67.6%)
|
75 (42%)
|
145 (81%)
|
128 (71%)
|
52 (29%)
|
ILC
|
15
|
10
|
12
|
3
|
12
|
IMC
|
9
|
5
|
9
|
6
|
3
|
- For nuclear Ep-ICD a cut off of ≥ 2 was used to determine positivity. For cytoplasmic Ep-ICD the cut off was ≥ 4. For membranous EpEx a cut off of ≥ 3 was considered positive.
- *1 LCIS was also included in the study (data not shown in table).