Implication of metastasis suppressor gene, Kiss-1 and its receptor Kiss-1R in colorectal cancer

BMC Cancer

Table 2 The correlation of mRNA expression of Kiss-1 and clinical parameters

Category		No.	Median	IQR	p	P ^a
T/N^b
	Normal	80	97	6-2345
	Tumour	94	35	1-2108	0.3775
Paired T/N^b
	Paired normal	68	82	6-2344
	Paired tumour	68	8	0-1855	0.1672
Location
	Left colon	22	624	173-1968
	Right colon	28	719	44-2000	0.899
	Transcolon^c	2	154	N/A	0.958
	Rectum	22	673	175-2522	0.907
Dukes classification
	A	7	5539	848-24856
	B	33	780	104-2272	0.043^d
	C	32	611	190-1221	0.015^d
Tumour stage
	T1	2	8000	N/A
	T2	10	1721	789-10369	1
	T3	40	639	71-1332	0.226	0.0381^d
	T4	18	592	215-1600	0.186
Lymph node involvement
	Node 0^e	39	872	213-2874
	Node 1^e	16	715	67-1428	0.326
	Node 2^e	15	609	200-643	0.045^d
TNM staging
	I	9	2081	814-20038
	II	30	756	122-2473	0.06
	III&IV	32	611	190-1221	0.009^d
Clinical outcome
	No invasion	50	835	127-2372
	Invasion	26	579	161-948	0.1907
	Disease free	35	759	84-2081
	Incidence	23	635	217-2187	0.8115
	No recurrence	58	735	89-2373
	Local recurrence	7	643	269-3718	0.604
	No metastasis	50	735	84-2522
	Metastasis	19	634.3	213-1463	0.92
	Alive	36	661	86-1876
	Death	22	572	195-1644	0.923

^aTumour (T), Normal (N). ^bTransverse colon. ^c p < 0.05. ^dNode 0 stands for no node involvement; Node 1 stands for 1 to 3 lymph nodes close to the bowel found to contain cancer cells; Node 2 stands for more than 3 lymph nodes found to contain cancer cells and further than 3cm away from the main tumor in the bowel or the presence of cancer cells in lymph nodes connected to the main blood vessels around the bowel.

ISSN: 1471-2407