Figure 1
From: Large differences in global transcriptional regulatory programs of normal and tumor colon cells
Normal and tumor regulatory networks. Inference and representation of normal (A) and tumor (B) regulatory networks. Both networks were inferred using microarray expression data from paired normal and tumor colon tissue obtained from the same set of individuals. Red nodes correspond to TFs and blue to non-TFs. Notice that a TF may also be the target gene of another TF. A global loss of transcriptional interactions in the tumor regulatory network is observed.