Table 1 Clinicopathologic correlation of ALDH1A1 expression in 216 gastric cancer
From: ALDH1A1 overexpression is associated with the progression and prognosis in gastric cancer
Characteristics | No. of patients | ALDH1A1 expression (%) | P-value | |
|---|---|---|---|---|
Negative | Positive | |||
Gender | ||||
Male | 140 | 64 (45.7%) | 76 (54.3%) | |
Female | 76 | 44 (57.9%) | 32 (42.1%) | 0.087 |
Age (years) | ||||
≤ 60 | 136 | 74 (54.4%) | 62 (45.6%) | |
> 60 | 80 | 34 (42.5%) | 46 (57.5%) | 0.091 |
Size (cm) | ||||
≤ 5.0 | 139 | 76 (54.7%) | 63 (45.3%) | |
> 5.0 | 77 | 32 (41.6%) | 45 (58.4%) | 0.065 |
Tumor site | ||||
Upper | 86 | 36 (41.9%) | 50 (58.1%) | |
Middle/Lower | 130 | 72 (55.4%) | 58 (44.6%) | 0.052 |
Differentiation | ||||
Well/Moderate | 96 | 41 (42.7%) | 55 (57.3%) | |
Poor | 120 | 67 (55.8%) | 53 (44.2%) | 0.055 |
Depth of invasion | ||||
T1/T2 | 81 | 58 (71.6%) | 23 (28.4%) | |
T3/T4 | 135 | 50 (37.0%) | 85 (63.0%) | < 0.001 |
Lymph node metastasis | ||||
Negative | 59 | 46 (78.0%) | 13 (22.0%) | |
Positive | 157 | 62 (39.5%) | 95 (60.5%) | < 0.001 |
Stages | ||||
I/II | 71 | 52 (73.2%) | 19 (26.8%) | |
III | 145 | 56 (38.6%) | 89 (61.4%) | < 0.001 |