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Figure 3 | BMC Cancer

Figure 3

From: Btbd7 contributes to reduced E-cadherin expression and predicts poor prognosis in non-small cell lung cancer

Figure 3

Investigation of E-cadherin and N-cadherin expression in non-small cell lung cancer (T) and lung tissues (N) using immunohistochemistry. Strong and entire membrane expression of E-cadherin was seen in normal bronchial epithelium. Membrane expression of E-cadherin was decreased in cancer cells. N-cadherin expression was commonly absent in normal bronchial epithelium. Diffuse cytoplasmic expression of N-cadherin was detected in cancer cells. Strong cytoplasmic Btbd7 expression was accompanied by reduced membrane E-cadherin expression and accumulation of N-cadherin in cytoplasm in cancer cells (Ă—400).

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