Figure 5

Comparative expression analyses of the HMGA2 and Lin28 genes and the let-7a and mir-98 miRNAs in human OSCC. The study included 5 non neoplastic control samples (green columns), 6 tumour samples (red columns) and 2 patient derived cell lines (brown columns). A: relative HMGA2/HPRT real time PCR. B: relative Lin28/HPRT real time PCR. C: relative let-7a/RNU6B real time PCR. D: relative mir-98/RNU6B real time PCR. Statistical analysis of the relative real time PCR results (Hypothesis Test) was performed with REST 2008 software tool. A p-value of <0.05 was considered statistically significant. * indicates a statistical significant expression deregulation of HMGA2 and/or Lin28 and/or let-7a and/or mir-98 when compared to non neoplastic control group; p-value is displayed next to *.