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Table 1 Relation between clinical and histological characteristics of pancreatic cancer patients and ASS expression

From: Arginine deiminase augments the chemosensitivity of argininosuccinate synthetase-deficient pancreatic cancer cells to gemcitabine via inhibition of NF-κB signaling

Characteristics ASS
Positive Negative
Median age (range) years 63 (47–78) 68 (44–83)
Sex (male:female) 11:8 10:6
Histological grade
I 3 (9%) 2 (6%)
II 12 (35%) 9 (26%)
III 4 (12%) 4 (12%)
Tumor size (cm)
≤ 3 6 (18%) 3 (9%)
> 3– ≤ 6 10 (29%) 11 (32%)
>6 3 (9%) 1 (3%)
Pathologic stage
I 3 (9%) 1 (3%)
II 11 (32%) 8 (24%)
III 2 (6%) 2 (6%)
IV 3 (9%) 4 (12%)
Lymph node metastasis
Positive 9 (26%) 13 (35%)
Negative 10 (29%) 2 (9%)*
Local invasion
Positive 7 (24%) 12 (29%)
Negative 12 (32%) 3 (15%)*
  1. *P < 0.05.