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Table 1 Relation between clinical and histological characteristics of pancreatic cancer patients and ASS expression

From: Arginine deiminase augments the chemosensitivity of argininosuccinate synthetase-deficient pancreatic cancer cells to gemcitabine via inhibition of NF-κB signaling

Characteristics

ASS

Positive

Negative

Median age (range) years

63 (47–78)

68 (44–83)

Sex (male:female)

11:8

10:6

Histological grade

I

3 (9%)

2 (6%)

II

12 (35%)

9 (26%)

III

4 (12%)

4 (12%)

Tumor size (cm)

≤ 3

6 (18%)

3 (9%)

> 3– ≤ 6

10 (29%)

11 (32%)

>6

3 (9%)

1 (3%)

Pathologic stage

I

3 (9%)

1 (3%)

II

11 (32%)

8 (24%)

III

2 (6%)

2 (6%)

IV

3 (9%)

4 (12%)

Lymph node metastasis

Positive

9 (26%)

13 (35%)

Negative

10 (29%)

2 (9%)*

Local invasion

Positive

7 (24%)

12 (29%)

Negative

12 (32%)

3 (15%)*

  1. *P < 0.05.