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Figure 3 | BMC Cancer

Figure 3

From: Arginine deiminase augments the chemosensitivity of argininosuccinate synthetase-deficient pancreatic cancer cells to gemcitabine via inhibition of NF-κB signaling

Figure 3

The effect of ADI on apoptosis-related proteins and cell cycle protein cyclin D1 in pancreatic cancer cells. A and B, Treatment with ADI (1 mU/mL) regulates the levels of antiapoptotic proteins XIAP and survivin, and pro-apoptotic proteins caspase-3 and caspase-9 in PANC-1 cells. *, P < 0.05 as compared with the control group (0 mU/mL ADI); NS, not significant. C, ADI does not alter the expression level of p53 and p21 proteins in PANC-1 cells, as compared with the control group. D and E, ADI does not alter the expression level of p53 and p21 proteins in BxPC-3 cells, as compared with the control group.

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