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Table 3 mtDNA copy number and glioma risk estimates by selected variables

From: Association of leukocyte mitochondrial DNA content with glioma risk: evidence from a Chinese case–control study

Variables Casesa(n) Controlsa(n) Adjusted ORb(95% CI) Pvalue
High Low High Low
Sex       
Male 198 43 122 119 4.85 (3.52 to 6.71) <0.001
Female 139 34 86 87 4.26 (2.83 to 5.94) <0.001
Age, years       
<47 167 37 103 103 4.81 (3.42 to 6.69) <0.001
≥47 170 40 105 103 4.84 (3.59 to 6.65) <0.001
Smoking status       
Never 275 43 166 163 4.92 (3.43 to 6.82) <0.001
Ever 62 34 42 43 1.98 (1.14 to 3.02) 0.014
Family history of cancer      
Yes 28 17 16 16 2.14 (1.19 to 3.36) 0.006
No 309 60 192 190 4.89 (3.36 to 6.84) <0.001
  1. 95% CI, 95% confidence interval; mtDNA, mitochondrial DNA; OR, odds ratio.
  2. aCases and controls were dichotomized based on the median value of controls.
  3. bAdjusted by age, sex, smoking status, family history of cancer and histology type where appropriate.