|
Variables
|
Casesa(n)
|
Controlsa(n)
|
Adjusted ORb(95% CI)
|
Pvalue
|
|---|
|
High
|
Low
|
High
|
Low
|
|---|
|
Sex
| | | | | | |
|
Male
|
198
|
43
|
122
|
119
|
4.85 (3.52 to 6.71)
|
<0.001
|
|
Female
|
139
|
34
|
86
|
87
|
4.26 (2.83 to 5.94)
|
<0.001
|
|
Age, years
| | | | | | |
|
<47
|
167
|
37
|
103
|
103
|
4.81 (3.42 to 6.69)
|
<0.001
|
|
≥47
|
170
|
40
|
105
|
103
|
4.84 (3.59 to 6.65)
|
<0.001
|
|
Smoking status
| | | | | | |
|
Never
|
275
|
43
|
166
|
163
|
4.92 (3.43 to 6.82)
|
<0.001
|
|
Ever
|
62
|
34
|
42
|
43
|
1.98 (1.14 to 3.02)
|
0.014
|
|
Family history of cancer
| | | | | |
|
Yes
|
28
|
17
|
16
|
16
|
2.14 (1.19 to 3.36)
|
0.006
|
|
No
|
309
|
60
|
192
|
190
|
4.89 (3.36 to 6.84)
|
<0.001
|
- 95% CI, 95% confidence interval; mtDNA, mitochondrial DNA; OR, odds ratio.
-
aCases and controls were dichotomized based on the median value of controls.
-
bAdjusted by age, sex, smoking status, family history of cancer and histology type where appropriate.
