Table 2 χ2 tests for identification of prognostic factors for metastasis

Sex

Male

21 (42.0)

29 (58.0)

0.31

Female

13 (31.7)

28 (68.3)

Age

≤ 14 years

12 (33.3)

24 (66.7)

0.52

> 15 years

22 (40.0)

33 (60.0)

Tumor site

Distal femur/Proximal tibia/Proximal humerus (Not exceeding the isthmus)

12 (21.1)

45 (78.9)

<0.001

Others

22 (67.4)

12 (35.3)

Laterality

Left

13 (32.5)

27 (67.5)

0.40

Right

21 (41.2)

30 (58.8)

Tumor size

≥ 8 cm

25 (40.3)

37 (59.7)

0.39

< 8 cm

9 (31.0)

20 (69.0)

Pathologic fracture at diagnosis

Yes

3 (60.0)

2 (40.0)

0.36^*

No

31 (36.0)

55 (64.0)

Skip lesion

Yes

2 (66.7)

1 (33.3)

0.55^*

No

32 (36.4)

56 (63.6)

Intracapsular extension

Yes

13 (65.0)

7 (35.0)

0.004

No

21 (29.6)

50 (70.4)

ALP at diagnosis

Elevated

26 (46.4)

30 (53.6)

0.02

Normal

8 (22.9)

27 (77.1)

LDH at diagnosis

Elevated

5 (55.6)

4 (44.4)

0.12^*

Normal

14 (26.4)

39 (73.6)

Histologic type

Osteoblastic/chondroblastic/fibroblastic

19 (29.2)

46 (70.8)

0.02

Others (mixed and nonconventional type)

9 (60.0)

6 (40.0)

Limb salvage surgery type

Without Pasteurization

28 (36.4)

49 (63.6)

0.64

With Pasteurization

6 (42.9)

8 (57.1)

Huvos grade

I & II

15 (57.7)

11 (42.3)

0.01

III & IV

19 (29.2)

46 (70.8)

Surgical resection

Complete

28 (32.9)

57 (67.1)

0.002^*

Incomplete

6 (100.0)

0 (0.0)