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Figure 4 | BMC Cancer

Figure 4

From: Epstein-Barr virus infection and clinical outcome in breast cancer patients correlate with immune cell TNF-α/IFN-γ response

Figure 4

Clinical outcome of 35 patients with BC (out of all 85 patients) and correlation with frequency of peripheral NK cells and cytokine production (16 healthy individuals enrolled as negative controls). Overall survival (A) in patients with TNF-α expression (MIF) by NK cells > the control group (solid green line) and < the control group (red dashed line). In this group of 35 patients, copies of EBV genomes were detected in PBMCs in 66%, and in tumor tissues in 17%. The clinical outcome of the 35 patients with BC and correlation with TNF- α expression by peripheral T cells. Overall survival (B) in patients with TNF-α expression (MIF) by T cells > the control group (solid green line) and < the control group (red dashed).

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