Table 1 Patient and tumor characteristics for the modified intention-to-treat population
Characteristic | LET (n = 66) mean ± SD or n and % | LET + ZOL (n = 65) mean ± SD or n and % | Total (n = 131) mean ± SD or n and % |
|---|---|---|---|
Age (years) | |||
Mean ± SD | 70.6 ± 8.3 | 71.1 ± 9.1 | 70.8 ± 8.7 |
Median (range) | 71.0 (54.0–89.0) | 70.0 (54.0–88.0) | 71.0 (54.0–89.0) |
Height (cm) | |||
Mean ± SD | 162.3 ± 6.7 | 162.5 ± 7.0 | 162.4 ± 6.8 |
Median (range) | 163 (150–185) | 163 (144–180) | 163 (144–185) |
Body weight (kg) | |||
Mean ± SD | 70.7 ± 12.9 | 71.6 ± 16.9 | 71.2 ± 15.0 |
Median (range) | 69.0 (47.0–114.0) | 70.0 (41.0–150.0) | 69.2 (41.0–150.0) |
BMI (kg/m2) | |||
Mean ± SD | 26.9 ± 4.8 | 27.0 ± 5.8 | 26.9 ± 5.3 |
Median (range) | 26.3 (17.0–40.4) | 26.2 (16.6–55.1) | 26.2 (16.6–55.1) |
Postmenopausal state: yes | 65 (100.0) | 66 (100.0) | 131 (100.0) |
Age group | |||
< 65 years | 15 (22.7) | 16 (24.6) | 31 (23.7) |
≥ 65 years | 51 (77.3) | 49 (75.4) | 100 (76.3) |
Ethnicity: Caucasian | 65 (100.0) | 66 (100.0) | 131 (100.0) |
Histological type | |||
Invasive ductal | 44 (66.7) | 48 (73.8) | 92 (70.2) |
Invasive lobular | 12 (18.2) | 8 (12.3) | 20 (15.3) |
Invasive ductal and lobular | 2 (3.0) | 3 (4.6) | 5 (3.8) |
Other | 8 (12.1) | 6 (9.2) | 14 (10.7) |
Grading | |||
G1 | 10 (15.2) | 10 (15.4) | 20 (15.3) |
G2 | 47 (71.2) | 46 (70.8) | 93 (71.0) |
G3 | 9 (13.6) | 8 (12.3) | 17 (13.0) |
GX | 0 (0.0) | 1 (1.5) | 1 (0.8) |
T staging | |||
T in situ | 1 (1.5) | 0 (0.0) | 1 (0.8) |
T1 | 6 (9.1) | 5 (7.9) | 11 (8.5) |
T2 | 48 (72.7) | 40 (63.5) | 88 (68.2) |
T3 | 8 (12.1) | 8 (12.7) | 16 (12.4) |
T4 | 3 (4.5) | 10 (15.9) | 13 (10.1) |
Data lacking | 0 | 2 | 2 |
N staging | |||
0 | 44 (66.7) | 36 (55.4) | 80 (61.1) |
1 | 20 (30.3) | 27 (41.5) | 47 (36.0) |
2 | 1 (1.5) | 0 (0.0) | 1 (0.8) |
X | 1 (1.5) | 2 (3.1) | 3 (2.3) |
M staging | |||
0 | 65 (98.5) | 65 (100) | 130 (99.2) |
X | 1 (1.5) | 0 (0) | 1 (0.8) |
Data lacking | 0 | ||
Estrogen receptor status | |||
Negative | 2 (3.0) | 2 (3.1) | 4 (3.1) |
Positive | 64 (97.0) | 63 (96.9) | 127 (96.9) |
Progesterone receptor status | |||
Negative | 7 (10.6) | 6 (9.2) | 13 (9.9) |
Positive | 59 (89.4) | 59 (90.8) | 118 (90.1) |
ECOG performance status | |||
0 | 42 (63.6) | 38 (58.5) | 80 (61.1) |
1 | 20 (30.3) | 24 (36.9) | 44 (33.6) |
2 | 4 (6.1) | 3 (4.6) | 7 (5.3) |
3 | 0 (0) | 0 (0.0) | 0 (0) |