Co-expression of putative stemness and epithelial-to-mesenchymal transition markers on single circulating tumour cells from patients with early and metastatic breast cancer

Table 4 Distribution of CTC phenotypes according to ALDH1 and TWIST co-expression in index patients with early and metastatic breast cancer

Patients		ALDH1high/TWISTnuc		ALDH1high/TWISTcyt/neg		ALDH1low/neg/TWISTnuc		ALDH1low/neg/TWISTcyt/neg
Early	*Total CTC No*	*CTC No* (%)		*CTC No* (%)		*CTC No* (%)		*CTC No* (%)
1	3	0	(0)	0	(0)	0	(0)	3	(100)
2	5	0	(0)	0	(0)	0	(0)	5	(100)
3	3	1	(33.3)	0	(0)	2	(66.7)	0	(0)
4	6	3	(50)	1	(16.7)	2	(33.3)	0	(0)
5	6	0	(0)	6	(100)	0	(0)	0	(0)
Metastatic
1	2	2	(100)	0	(0)	0	(0)	0	(0)
2	11	10	(90.9)	1	(9.1)	0	(0)	0	(0)
3	2	1	(50)	0	(0)	1	(50)	0	(0)
4	3	1	(20)	2	(80)	0	(0)	0	(0)
5	21	5	(23.8)	14	(66.7)	0	(0)	2	(9.5)
6	2	0	(0)	0	(0)	0	(0)	2	(100)
7	11	3	(27.2)	2	(18.2)	6	(54.5)	0	(0)

ISSN: 1471-2407