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Table 4 Distribution of CTC phenotypes according to ALDH1 and TWIST co-expression in index patients with early and metastatic breast cancer

From: Co-expression of putative stemness and epithelial-to-mesenchymal transition markers on single circulating tumour cells from patients with early and metastatic breast cancer

Patients   ALDH1high/TWISTnuc ALDH1high/TWISTcyt/neg ALDH1low/neg/TWISTnuc ALDH1low/neg/TWISTcyt/neg
Early Total CTC No CTC No (%) CTC No (%) CTC No (%) CTC No (%)
1 3 0 (0) 0 (0) 0 (0) 3 (100)
2 5 0 (0) 0 (0) 0 (0) 5 (100)
3 3 1 (33.3) 0 (0) 2 (66.7) 0 (0)
4 6 3 (50) 1 (16.7) 2 (33.3) 0 (0)
5 6 0 (0) 6 (100) 0 (0) 0 (0)
Metastatic
1 2 2 (100) 0 (0) 0 (0) 0 (0)
2 11 10 (90.9) 1 (9.1) 0 (0) 0 (0)
3 2 1 (50) 0 (0) 1 (50) 0 (0)
4 3 1 (20) 2 (80) 0 (0) 0 (0)
5 21 5 (23.8) 14 (66.7) 0 (0) 2 (9.5)
6 2 0 (0) 0 (0) 0 (0) 2 (100)
7 11 3 (27.2) 2 (18.2) 6 (54.5) 0 (0)