Table 2 Correlations of DR with clinicopathologic features
From: Peritumoral ductular reaction: a poor postoperative prognostic factor for hepatocellular carcinoma
|  | DR (<2 vs ≥2) | ||||
|---|---|---|---|---|---|
Variable | Â | Low (%) | High (%) | p | |
Age (year) (median; 25 and 75 percentiles) | 50; 40-59 | ≤50 | 13 (50.0) | 43 (53.8) | 0.379 |
>50 | 13 (50.0) | 37 (46.2) | |||
Gender | Â | Male | 22 (84.6) | 66 (82.5) | 0.534 |
Female | 4 (15.4) | 14 (17.5) | |||
ALT (U/L) (median; 25 and 75 percentiles) | 44.6; 29.9-72 | ≤40 | 16 (61.5) | 28 (35.0) | 0.017 |
>40 | 10 (38.5) | 52 (65.0) | |||
γ-GT (U/L) (median; 25 and 75 percentiles) | 74.6; 46.4-106.8 | ≤55 | 13 (50.0) | 24 (30.0) | 0.063 |
>55 | 13 (50.0) | 56 (70.0) | |||
ALP (U/L) (median; 25 and 75 percentiles) | 145; 116.5-190 | ≤121 | 13 (50.0) | 18 (22.5) | 0.007 |
>121 | 13 (50.0) | 62 (77.5) | |||
AFP (ng/ml) (median; 25 and 75 percentiles) | 325; 40.9-1000 | ≤20 | 11 (42.3) | 14 (17.5) | 0.010 |
>20 | 15 (57.7) | 66 (82.5) | |||
HBsAg state | Â | Negative | 10 (38.5) | 6 (7.5) | 4.9E-04 |
Positive | 16 (61.5) | 74 (92.5) | |||
Tumor size (cm) (median; 25 and 75 percentiles) | 7; 4.6-11.8 | ≤5 | 7 (26.9) | 28 (35.0) | 0.447 |
>5 | 19 (73.1) | 52 (65.0) | |||
Tumor number | Â | Single | 25 (96.2) | 54 (67.5) | 0.004 |
Multiple | 1 (3.8) | 26 (32.5) | |||
Tumor capsule | Â | Yes | 10 (38.5) | 14 (17.5) | 0.027 |
None | 16 (61.5) | 66 (82.5) | |||
Vascular invasion | Â | No | 18 (69.2) | 52 (65.0) | 0.692 |
Yes | 8 (30.8) | 28 (35.0) | |||
Microscopic vascular invasion (mean ± SD)* | 4.3 ± 3.5 | ≤5 | 7 (87.5) | 10 (35.7) | 0.031 |
>5 | 1 (12.5) | 18 (64.3) | |||
BCLC stage (A/B/C) | 39/12/55 | A | 16 (61.5) | 23 (28.8) | 0.003 |
B/C | 10 (38.5) | 57 (71.2) | |||
TNM stage (I/II/III) | 35/23/48 | I | 15 (57.7) | 20 (25.0) | 0.002 |
II/III | 11 (42.3) | 60 (75.0) | |||
Recurrence** | Â | Early | 8 (47.1) | 52 (65.0) | 0.010 |
| Â | Â | Late | 9 (52.9) | 12 (35.0) | Â |