Immunostaining of DR, histopathology of HPCs and intermediate hepatocytes in fibrotic tissue or peritumoral and tumoral tissues. (A, B, C) DR emanated from the portal zone and expanded into the parenchyma of proliferative nodules, HPCs (arrowheads) and intermediate hepatocytes (arrows) can be seen in the nodules. (D, E, F) DR and CK-19 positive tumor (in dashed line) that had no capsule were shown. HPC (arrowhead) was close to DR, intermediate hepatocytes (arrows) were between DR and neoplastic nodule. (A and D 100×; B and E 200×; C and F 400×).