Figure 3From: Differential subcellular and extracellular localisations of proteins required for insulin-like growth factor- and extracellular matrix-induced signalling events in breast cancer progression Stromal immunoreactivity of SFN. Immunoreactivity of SFN within the stroma surrounding normal breast (Normal), primary cancer (Primary) and LN metastasis tissues is depicted. Immunoreactivity was evaluated semiquantitatively using the Q score (intensity x percentage class, score: 0 – 18) method. Intensity of reactivity (score: 0 = negative; 1 = weak; 2 = moderate, and; 3 = strong). Percentage class (score: 1 = 0-4%; 2 = 5-19%; 3 = 20-39%; 4 = 40-59%; 5 = 60-79%; 6 = 80-100%). Data are displayed using the mean ± 2 standard error (SE). Asterisks (* and ***) indicate statistically significant differences at p < 0.05 and <0.001, respectively. Scale bar = 30 μm.Back to article page