pERK, pAKT and p53 as tissue biomarkers in erlotinib-treated patients with advanced pancreatic cancer: a translational subgroup analysis from AIO-PK0104

Table 5 Correlation of biomarkers results with the occurrence of skin rash (any grades, I-III)

Biomarker	n	Skin rash [%]		p
		No rash	Any rash (grade I-III)
p-ERK	153
pERK ^low	55	29	71	0.41
pAKT ^high	98	36	64
p-AKT	35
pERK ^low	21	33	67	0.49
pAKT ^high	14	46	54
p53	50
Loss	4	75	25	0.04⁺
Regular	20	16	84
Overexpression	26	39	61

ISSN: 1471-2407