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Table 5 Published study on SBRT for oligometastases from CRC

From: Stereotactic Ablative Radiotherapy (SABR) in inoperable oligometastatic disease from colorectal cancer: a safe and effective approach

Author, design study, (reference) Patients (n) Lesions (n) Dose (Gy/ fr) FUP (m) LC (%) OS (%) Median PFS (m) Acute Toxicity ≥G3
1-year 2-yeras 1-year 2-years
Hoyer, Phase II (27) 44 - 45 Gy/3 fr 4.3 y 90% 79% 67% 38% 6.5 48%
Van der Pool, Phase I-II (28) 20 31 37.5 Gy/3 fr 26 m 100% 74% 100% 83% 11 10%
45 Gy/3 fr
(2 pts)
Kang, Retrospective (29) 59 78 36–51 Gy/3 fr 32 m 85% 66% 82% 66% - 3%
14 Gy/1 fr
Bae Retrospective (30) 41 50 45–60 gy/3 fr 28 m 100% 85% 85% 70% - 7%
Current Study 82 112 48 Gy/4 fr 24m 85% 70% 85% 65% 14m 0%
60–75 Gy/3 fr 97% 92%