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Figure 6 | BMC Cancer

Figure 6

From: Vasculotide, an Angiopoietin-1 mimetic, reduces acute skin ionizing radiation damage in a preclinical mouse model

Figure 6

VT and Ang1 increase survival and function of irradiated immortalized human microvascular endothelial cells. (A) In vitro HMVEChTERT clonogenic survival with 28 ng ml−1 VT (left) or 200 ng ml−1 Ang1 (right). Expressed as mean ± SD and SERs are indicated. (B) Micrographs of HMVEChTERT tubule formation on Matrigel 6 h after plating (left, scale bars = 500 μm). Cells were pre-treated with PBS, 28 ng ml−1 VT or 200 ng ml−1 Ang1, and 0 or 4 Gy, and results are graphed (right). Expressed as mean ± SD. * represents P < 0.05, ** represents P < 0.01, “ns” represents ‘not significant’.

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