Figure 1
From: Variable NF-κB pathway responses in colon cancer cells treated with chemotherapeutic drugs
Generation and testing of NF-κB reporter cells. A: schematic representation of NF-κB reporter constructs; NC-L = negative control luciferase, NF-L = NF-κB luciferase. B, C, and D: relative NF-κB activity indices for reporter SW480, wild type HCT116, and p53-null HCT116 colon cancer cells, respectively. Grey bars = unstimulated; black bars = TNF-stimulated (at 100 ng/ml concentration).