post-RT ambulatory rate (%) | p-value | Scoring points | |
---|---|---|---|
Age | |||
65-70 years (n = 230) | 70 | 7 | |
71-80 years (n = 266) | 65 | 7 | |
≥ 81 years (n = 69) | 48 | 0.004 | 5 |
Gender | |||
Female (n = 197) | 73 | ||
Male (n = 368) | 61 | 0.15 | |
Type of primary tumor | |||
Breast cancer (n = 89) | 85 | 9 | |
Prostate cancer (n = 150) | 61 | 6 | |
Myeloma/lymphoma (n = 51) | 88 | 9 | |
Lung cancer (n = 112) | 66 | 7 | |
Cancer of unknown primary (n = 44) | 36 | 4 | |
Renal cell carcinoma (n = 34) | 68 | 7 | |
Colorectal cancer (n = 28) | 39 | 4 | |
Other tumors (n = 57) | 54 | 0.002 | 5 |
Number of involved vertebrae | |||
1-2 (n = 235) | 70 | ||
3-4 (n = 191) | 64 | ||
≥ 5 (n = 139) | 58 | 0.28 | |
Ambulatory status prior to RT | |||
Not Ambulatory (n = 234) | 24 | 2 | |
Ambulatory (n = 331) | 94 | <0.001 | 9 |
Other bone metastases | |||
No (n = 229) | 72 | ||
Yes (n = 336) | 60 | 0.64 | |
Visceral metastases | |||
No (n = 319) | 74 | 7 | |
Yes (n = 246) | 53 | 0.017 | 5 |
Interval from cancer diagnosis to RT of MSCC | |||
≤ 15 months (n = 290) | 58 | ||
> 15 months (n = 275) | 73 | 0.18 | |
Time developing motor deficits | |||
1-7 days (n = 175) | 30 | 3 | |
8-14 days (n = 140) | 70 | 7 | |
> 14 days (n = 250) | 87 | <0.001 | 9 |
Radiation regimen | |||
1 × 8 Gy (n = 96) | 68 | ||
5 × 4 Gy (n = 154) | 60 | ||
10 × 3 Gy (n = 151) | 60 | ||
15 × 2.5 Gy (n = 64) | 66 | ||
20 × 2 Gy (n = 100) | 77 | 0.71 |