Figure 2

Comparison of the diagnostic performance of serum MIC-1, CA19.9, CEA and CA242 for PDAC. a. Sensitivities and specificities of MIC-1 , CA19.9, CEA and CA242 for the diagnosis of PDAC was compared through the analyses of ROC curves in the discovery group (n = 1307). AUROC curve of serum MIC-1 was much larger than that of CA19.9, CEA and CA242 (P < 0.001). b. The potential of serum MIC-1 for distinguishing CA19.9-negative pancreatic carcinomas from non–pancreatic carcinoma controls including benign pancreas tumors. c. A similar positive rate (present above the bar) of serum MIC-1 (using the cut off value 1000 pg/mL) was observed in patients with PDAC with different CA19.9 levels.