Figure 3
CDK11 p58 downregulates integrin β3 in ERα-positive breast cancer cells. (A) Overexpression of CDK11p58 in MCF-7 ER-positive breast cancer cells. The expression of CDK11p58 was detected by qRT-PCR and western blotting. (B) Genes downregulated in the metastasis pathway in the TaqMan Array human metastasis gene expression assay. (C) Genes upregulated in the metastasis pathway in the TaqMan Array human metastasis gene expression assay. (D) Validation of TaqMan Array human gene expression assays by qRT-PCR.