Figure 7

Treatment with 4 delays migration rate of MDA-MB-231 cells in vitro . A scratch was introduced in the culture dish and the cells were left treated (3 mM and 1 mM) or untreated for 22 h. Photo micrographic as well as time-lapse video micrographic images were captured to study relative migration capacity of control or drug treated MDA-MB-231 cells. (a) At 3 mM concentration, cells treated with NS covered 66% of the gap, whereas, 4, could cover only 6% of the gap. (b) Video micrographic images indicating migration rates of control or treated MDA-MB-231 cells during 22 h. (c) Graph indicating distance travelled/h of control or treated MDA-MB-231 cells during 22 h. Each point on the graph represents Mean ± SD, p values of t-test are indicated on top of horizontal bars. n = 3.