BMC Cancer

Table 1 Cytotoxicities of several drugs against KB and CDDP-resistant cell line, KB/CDDP(T)

From: 3'-Ethynylcytidine, an RNA polymerase inhibitor, combined with cisplatin exhibits a potent synergistic growth-inhibitory effect via Vaults dysfunction

	ECyd		CDDP		CBDCA		ADM		SN-38
Cell line	IC₅₀	Fold	IC₅₀	Fold	IC₅₀	Fold	IC₅₀	Fold	IC₅₀	Fold
Cell line	μmol/L	Fold	μmol/L	Fold	μmol/L	Fold	μmol/L	Fold	μmol/L	Fold
KB	0.022	1.0	0.82	8.4	28.40	7.5	0.022	3.8	0.002	35
KB/CDDP(T)	0.022	1.0	6.92	8.4	214.13	7.5	0.084	3.8	0.070	35

Cells were exposed to each drug for 72 hr. Data are shown as the mean (n = 4).

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