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Figure 2 | BMC Cancer

Figure 2

From: 3'-Ethynylcytidine, an RNA polymerase inhibitor, combined with cisplatin exhibits a potent synergistic growth-inhibitory effect via Vaults dysfunction

Figure 2

Silencing of MVP increases the cellular sensitivity to CDDP. A) The basal expression of MVP protein in KB/CDDP(T) cells and parental cells was analyzed using immunoblot analysis. B) The expression of MVP protein in KB/CDDP(T) cells treated with siRNA to MVP or negative control siRNA was analyzed using immunoblot analysis. Equal loading was confirmed by the detection of β-actin. C) The expression of MVP protein in KB/CDDP(T) cells treated with siRNA to MVP or negative control siRNA was analyzed using immunocytochemistry. D) The sensitivity of KB/CDDP(T) and parental cells treated with siRNA to MVP or negative control siRNA against CDDP was analyzed. Data are shown as the mean (n = 4).

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BMC Cancer

ISSN: 1471-2407

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