Table 2 Guidelines that mention DARE as a means for anal cancer screening
Guidelines | Recommendation | Target population | Frequency of DARE | Level of evidence |
|---|---|---|---|---|
European AIDS Clinical Society Guidelines [33] | ‘digital rectal exam +/- Papanicolau test’ | HIV positive MSM | Every 1–3 years | III (expert opinion) |
US Guideline for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents [38] | ‘digital rectal examination as an important procedure to detect masses on palpation that might be anal cancer’ | Not specified | Annually | III |