Skip to main content

Table 2 Association of API5 and pERK1/2 expression in cervical cancer and CIN patients

From: Apoptosis inhibitor-5 overexpression is associated with tumor progression and poor prognosis in patients with cervical cancer

 

API5 expression

 

Low (-)

%

High (+)

%

Total no.

Pvalue

Cancer

85

65.9

44

34.1

129

P < 0.001

pERK1/2 (-)

69

75.8

22

24.2

91

 

pERK1/2 (+)

16

42.1

22

57.9

38

 

High grade CIN

170

89.9

19

10.1

189

P = 0.031

pERK1/2 (-)

106

93.8

7

6.2

113

 

pERK1/2 (+)

64

84.2

12

15.8

76

 

Low grade CIN

51

96.2

2

3.8

53

P = 0.301

pERK1/2 (-)

33

94.3

2

5.7

35

 

pERK1/2 (+)

18

100.0

0

0.0

66

 
  1. API5+, IHC score of ≥ 8; pERK1/2+, IHC score of ≥ 4.