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Table 2 Association of API5 and pERK1/2 expression in cervical cancer and CIN patients

From: Apoptosis inhibitor-5 overexpression is associated with tumor progression and poor prognosis in patients with cervical cancer

  API5 expression
  Low (-) % High (+) % Total no. Pvalue
Cancer 85 65.9 44 34.1 129 P < 0.001
pERK1/2 (-) 69 75.8 22 24.2 91  
pERK1/2 (+) 16 42.1 22 57.9 38  
High grade CIN 170 89.9 19 10.1 189 P = 0.031
pERK1/2 (-) 106 93.8 7 6.2 113  
pERK1/2 (+) 64 84.2 12 15.8 76  
Low grade CIN 51 96.2 2 3.8 53 P = 0.301
pERK1/2 (-) 33 94.3 2 5.7 35  
pERK1/2 (+) 18 100.0 0 0.0 66  
  1. API5+, IHC score of ≥ 8; pERK1/2+, IHC score of ≥ 4.