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Table 1 Factors affecting complications and high-grade complications after IRE (vascular invasion)

From: Irreversible electroporation of unresectable soft tissue tumors with vascular invasion: effective palliation

 

Complications (# Pts with complications)

High-Grade complications

Univariate analysis (p value)*

Multivariate

Hazard ratio

95% Confidence interval

p value

#Pts with PMH cardiac (n = 16pts)

6 (38%)

2 (13%)

0.4/0.7

   

#Pts with PMH Diabetes (26pts)

8 (31%)

2

0.009/0.05^

4.0

1.4-11

0.007^

#Pts with Tobacco use (40 pts)

12 (30%)

4

0.2/0.5

   

#Pts with Pancreas IRE(59 pts)

30 (51%)

12

0.01/0.4^

3.2

1.3-7

0.01^

#Pts with Open IRE (60 pts)

34 (57%)

13

0.00/0.00^

5.8

1.4-11

0.02^

#Pts with Major Abdominal Procedure (56 pts)

27 (48%)

15

0.03/0.2^

0.8

0.3-1.8

0.5

#Pts with Radiation (67 pts)

21 (31%)

16

0.02/0.09^

3.6

1.3-9

0.01^

#Pts with prior Intra-arterial Rx# (21 pts)

2 (10%)

1

0.3/0.4

   

#Pt with prior ChemoRx (106 pts)

30 (28%)

11

0.8/0.4

   

Size of lesion > 3 cm

26 (36.1%)

9 (12.5%)

0.01/0.4^

1.3

0.6-1.9

0.8

  1. # Intra-arterial emboic therapy (SIRS, TACE, Bland), ^Higher risk of complications.
  2. *Univariate analysis: 1st value is p value for complications, 2nd value is p for high-grade complications.