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Table 1 Factors affecting complications and high-grade complications after IRE (vascular invasion)

From: Irreversible electroporation of unresectable soft tissue tumors with vascular invasion: effective palliation

  Complications (# Pts with complications) High-Grade complications Univariate analysis (p value)* Multivariate
Hazard ratio 95% Confidence interval p value
#Pts with PMH cardiac (n = 16pts) 6 (38%) 2 (13%) 0.4/0.7    
#Pts with PMH Diabetes (26pts) 8 (31%) 2 0.009/0.05^ 4.0 1.4-11 0.007^
#Pts with Tobacco use (40 pts) 12 (30%) 4 0.2/0.5    
#Pts with Pancreas IRE(59 pts) 30 (51%) 12 0.01/0.4^ 3.2 1.3-7 0.01^
#Pts with Open IRE (60 pts) 34 (57%) 13 0.00/0.00^ 5.8 1.4-11 0.02^
#Pts with Major Abdominal Procedure (56 pts) 27 (48%) 15 0.03/0.2^ 0.8 0.3-1.8 0.5
#Pts with Radiation (67 pts) 21 (31%) 16 0.02/0.09^ 3.6 1.3-9 0.01^
#Pts with prior Intra-arterial Rx# (21 pts) 2 (10%) 1 0.3/0.4    
#Pt with prior ChemoRx (106 pts) 30 (28%) 11 0.8/0.4    
Size of lesion > 3 cm 26 (36.1%) 9 (12.5%) 0.01/0.4^ 1.3 0.6-1.9 0.8
  1. # Intra-arterial emboic therapy (SIRS, TACE, Bland), ^Higher risk of complications.
  2. *Univariate analysis: 1st value is p value for complications, 2nd value is p for high-grade complications.
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