Figure 1
From: Hypoxia represses microRNA biogenesis proteins in breast cancer cells
Dicer protein expression in hypoxia vs. normoxia. Dicer protein expression was examined in SKBR3, MCF7 and HUVEC cells after exposure to different O2 concentrations for different durations. A, Dicer protein expression in SKBR3 cells after exposure to 0.1% O2 for 16 h and B, 24 h. C, Dicer protein expression in MCF7 cells after exposure to 0.1% O2 for 48 h. D, Dicer protein expression in SKBR3 cells after exposure to 0.1% O2 for 48 h. E, Dicer protein expression in SKBR3 cells after exposure to 1% O2 for 72 h. F, Dicer protein expression in HUVECs after exposure to 1% O2 for 24 h. G, Dicer protein expression in HUVECs after exposure to 1% O2 for 48 h (P = 0.1). Dicer and α-actinin protein expression was examined by immunoblotting. Results show three technical replicates per treatment.