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Table 1 Patient characteristics of the study cohort

From: Histone trimethylation at H3K4, H3K9 and H4K20 correlates with patient survival and tumor recurrence in early-stage colon cancer

 

Study cohort

Colon stage I + II

(n = 254)

(n = 121)

 

N

(%)

n

(%)

Age at randomization

   

 <50

32

12.6

11

9.1

 50-75

161

63.4

80

66.1

 >75

61

24

30

24.8

Gender

  

 Male

128

50.4

61

50.4

 Female

126

49.6

60

49.6

TNM stage

  

 I

53

20.9

30

24.8

 II

113

44.5

91

75.2

 III

88

34.6

  

Tumor location

    

 Colon

187

73.6

121

100

 Rectum

67

26.4

  

Tumor size

  

 Mean

4.69

4.57

 Standard error

2.32

0.21

MSS status

    

 MSS

175

68.9

20

16.5

 MSI

34

13.4

75

62

 Unknown

45

17.7

26

21.5

Tumor in follow up

    

 No

215

84.6

105

86.8

 Yes

39

15.4

16

13.2

Adjuvant therapy

    

 No

206

81.1

117

96.7

 Yes

48

18.9

4

3.3

  1. Patient characteristics are shown for both the study cohort (n = 254) and the patients with TNM stage I and II colon cancer as used for the statistical analyses (n = 121). Patient selection was based on availability of FFPE tissues, available data for all three markers, and information about the listed covariables. The study cohort selection was representative for the entire colorectal cancer series.