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Table 1 Patient characteristics of the study cohort

From: Histone trimethylation at H3K4, H3K9 and H4K20 correlates with patient survival and tumor recurrence in early-stage colon cancer

  Study cohort Colon stage I + II
(n = 254) (n = 121)
  N (%) n (%)
Age at randomization    
 <50 32 12.6 11 9.1
 50-75 161 63.4 80 66.1
 >75 61 24 30 24.8
Gender   
 Male 128 50.4 61 50.4
 Female 126 49.6 60 49.6
TNM stage   
 I 53 20.9 30 24.8
 II 113 44.5 91 75.2
 III 88 34.6   
Tumor location     
 Colon 187 73.6 121 100
 Rectum 67 26.4   
Tumor size   
 Mean 4.69 4.57
 Standard error 2.32 0.21
MSS status     
 MSS 175 68.9 20 16.5
 MSI 34 13.4 75 62
 Unknown 45 17.7 26 21.5
Tumor in follow up     
 No 215 84.6 105 86.8
 Yes 39 15.4 16 13.2
Adjuvant therapy     
 No 206 81.1 117 96.7
 Yes 48 18.9 4 3.3
  1. Patient characteristics are shown for both the study cohort (n = 254) and the patients with TNM stage I and II colon cancer as used for the statistical analyses (n = 121). Patient selection was based on availability of FFPE tissues, available data for all three markers, and information about the listed covariables. The study cohort selection was representative for the entire colorectal cancer series.