Table 3 Interaction of overall survival (OS) and disease-free survival (DFS) with histopathological variables
OS | DFS | ||||
|---|---|---|---|---|---|
Variables | Mean (95% CI) | p value | Mean (95% CI) | p value | |
Sex | Male | 72.08 (62.61-81.55) | 0.103 | 52.15 (42.12-62.18) | 0.179 |
Female | 79.52 (71.55-87.50) | 61.00 (49.16-72.85) | |||
Differentiation grade | Well-moderate | 77.62 (70.03-85.21) | 0.408 | 56.25 (47.45-65.06) | 0.649 |
Poor | 64.14 (48.53-79.75) | 56.50 (38.35-74.64) | |||
Tumor stage | I-II | 80.75 (71.71-89.78) | 0.167 | 70.31 (59.84-80.78) | 0.002* |
III-IV | 68.89 (58.72-79.05) | 42.44 (32.30-52.58) | |||
MGMT methylation status | Unmethylated | 73.54 (65.17-81.90) | 0.398 | 49.87 (34.54-65.20) | 0.949 |
Methylated | 76.07 (67.82-84.32) | 57.33 (47.55-67.12) | |||
Percentage MGMT expression | Low | 70.53 (60.02-81.05) | 0.211 | 50.77 (39.35-62.20) | 0.328 |
High | 77.04 (69.58-84.50) | 58.62 (48.37-68.87) | |||
MGMT expression intensity | Low | 61.36 (45.99-76.72) | 0.006* | 47.76 (32.80-62.71) | 0.171 |
High | 77.48 (70.75-84.21) | 56.43 (47.39-65.47) | |||
Percentage CD133 expression | Low | 82.03 (72.97-91.10) | 0.273 | 67.91 (56.68-79.14) | 0.014* |
High | 70.41 (61.33-79.50) | 46.01 (35.06-56.97) | |||
CD133 expression intensity | Low | 77.90 (69.39-86.41) | 0.642 | 59.76 (49.62-69.89) | 0.517 |
High | 78.00 (67.92-88.08) | 53.74 (39.44-68.05) | |||
High MGMT intensity | CD133 ≥ 50% | 73.06 (63.99-82.14) | 0.032* | 49.14 (36.25-62.04) | 0.140 |
CD133 < 50% | 72.33 (61.82-82.84) | 57.08 (44.64-69.51) | |||
Low MGMT intensity | CD133 ≥ 50% | 52.36 (30.53-74.19) | 37.85 (18.87-56.83) | ||
CD133 < 50% | 69.50 (45.88-93.11) | 64.50 (41.41-87.59) | |||