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Table 2 Validation of relative bias of five-year extrapolation based on actual 10-year survival using Kaplan-Meier (K-M) estimates as the gold standard

From: Estimation of savings of life-years and cost from early detection of cervical cancer: a follow-up study using nationwide databases for the period 2002–2009

Stage Cohort size Mean age at diagnosis (SD)* Censored rate (%) 10-year survival based on K-M estimate in years (SE) Extrapolation based on the first five-year follow up in years (SE) Relative bias (%)
1 3,823 52.49 (13.20) 92.68 8.60 (0.05) 8.47 (0.02) −1.57
2 1,791 60.39 (13.99) 80.07 6.76 (0.10) 6.69 (0.05) −1.05
3 680 61.65 (14.91) 58.38 4.69 (0.15) 4.53 (0.08) −3.57
4 373 60.40 (14.69) 39.68 2.71 (0.15) 2.45 (0.10) −9.54
  1. *SD, standard deviation; SE, standard error of mean.
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