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Table 1 Description of the common chemotherapy regimens used in the series

From: An effective and well-tolerated strategy in recurrent and/or metastatic head and neck cancer: successive lines of active chemotherapeutic agents

Platinum based regimens (name and dose)

Platinum free regimens (name and dose)

Cisplatin (100 mg/m2/3 weeks) + 5-FU (1000 mg/m2/d, 5 days/3 weeks)

Paclitaxel (60 to 80 mg/m2/week) + Cetuximab (400 mg/m2 then 250 mg/m2/week)

Cisplatin (75 mg/m2/3 weeks) + Docetaxel (75 mg/m2/3 weeks)

Paclitaxel (80 mg/m2/week)

Cisplatin (75 mg/m2/3 weeks) + Docetaxel (75 mg/m2/3 weeks) + Cetuximab (400 mg/m2 then 250 mg/m2/week)

Methotrexate (40 mg/m2/week)

Cisplatin (75 mg/m2/3 weeks) + Docetaxel (75 mg/m2/3 weeks) + 5-FU (750 mg/m2/d, 5 days/3 weeks)

Capecitabine (1,000 mg/m2 BID for 14 days/21 days)

Cisplatin (100 mg/m2/3 weeks) + 5-FU (1000 mg/m2/d, 4 days/3 weeks) + Cetuximab (400 mg/m2 then 250 mg/m2/week)

 

Carboplatin (AUC5/3 weeks) + 5-FU (1000 mg/m2/d, 4 days/3 weeks) + Cetuximab (400 mg/m2 then 250 mg/m2/week)

 

Carboplatin (AUC5/3 weeks) + Paclitaxel (80 mg/m2/week)

 

Carboplatin (AUC5/3 weeks)

 
  1. 5-FU = 5-Fluorouracil.
  2. AUC = Area Under the Curve.
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BMC Cancer

ISSN: 1471-2407

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