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Table 3 Combined effect of rs2074356 and rs2274223 on the risk of ESCC

From: HPV seropositivity joints with susceptibility loci identified in GWASs at apoptosis associated genes to increase the risk of Esophageal Squamous Cell Carcinoma (ESCC)

Rs2074356

Rs2274223

Cases (n = 313)

Controls (n = 314)

AdjustedP value

Adjusted OR (95% CI)*

  

No.

%

No

%

  

CC

AA

109

34.8

146

46.5

 

1

CC

GG/AG

87

27.8

81

25.8

0.024

1.60 (1.06-2.42)

CT/TT

AA

63

20.1

63

20.1

0.211

1.33 (0.85-2.08)

CT/TT

GG/AG

54

17.3

24

7.6

<0.001

3.31 (1.87-5.83)

Rs2074356*rs2274223

    

0.002

1.26 (1.09-1.45)

  1. *ORs were adjusted for age, sex, smoking and drinking in logistic regression models.
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BMC Cancer

ISSN: 1471-2407

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