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Table 1 Distribution of demographic variables and risk factors in esophageal squamous cell cancer cases and cancer-free control subjects

From: HPV seropositivity joints with susceptibility loci identified in GWASs at apoptosis associated genes to increase the risk of Esophageal Squamous Cell Carcinoma (ESCC)

Characteristics

Cases (n = 313)

Controls (n = 314)

P values

OR (95% CI)*

 

Number

(%)

Number

(%)

  

Age (years)

    

0.247

 

<58

152

(48.6)

167

(53.2)

 

1

≥58

161

(51.4)

147

(46.8)

 

1.20 (0.88-1.65)

Sex

    

0.673

 

Female

47

(15.0)

51

(16.2)

 

1

Male

266

(85.0)

263

(83.8)

 

1.10 (0.71-1.69)

Tobacco smoking

    

<0.001

 

Never

92

(29.4)

158

(50.3)

 

1

Ever

221

(70.6)

156

(49.7)

 

2.43 (1.75-3.38)

Alcohol drinking

    

0.001

 

Never

115

(36.7)

156

(49.7)

 

1

Ever

198

(63.3)

158

(50.3)

 

1.70 (1.24-2.34)

HPV status

      

-

143

(45.7)

178

(56.7)

0.006

1

+

170

(54.3)

136

(43.3)

 

1.56 (1.14-2.13)

  1. P values for cases vs. controls were calculated with two-sided χ2 tests.
  2. *ORs were assessed in logistic regression models.