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Table 3 Cox uni-and multivariable analysis of relative risk of death from colorectal cancer, rectal cancer, and left hemicolon cancer within 5 years by HES9 expression

From: Podocalyxin is a marker of poor prognosis in colorectal cancer

  Colorectal cancer-specific survival Left hemicolon cancer-specific survival Rectal cancer-specific survival
  HR (95% CI) p-value n (events) HR (95% CI) p-value n (events) HR (95% CI) p-value n (events)
  Univariable         
HES9 low 1.00   723 (266) 1.00   534 (194) 1.00   351 (125)
   High 2.00 (1.31–3.06) 0.001 44 (23) 2.60 (1.45–4.66) 0.001 21 (12) 3.03 (1.54–5.60) 0.001 16 (9)
  Multivariable         
HES9 low 1.00   719 (266) 1.00   532 (194) 1.00   351 (125)
   High 1.82 (1.15–2.86) 0.01 44 (23) 2.59 (1.41–4.88) 0.002 21 (12) 2.69 (1.30–5.54) 0.007 16 (9)
  1. Abbreviations: CI confidence interval, HR Hazard ratio. Multivariable analysis included adjustment for gender, age (>/≤65 years), Dukes class, differentiation grade (G1/2 vs G3/4). MAb HES9 recognises PODXL protein.