Table 2 Diagnostic values, including sensitivity, specificity, positive predictive value and negative predictive value, combining assay seromarkers
Combinations | Sensitivity(%) | Specificity(%) | PPV(%) | NPV(%) |
|---|---|---|---|---|
YKL-40 | 72.70 | 84.13 | 84.50 | 72.11 |
CEA | 8.00 | 96.80 | 75.00 | 46.72 |
CYFRA21-1 | 40.00 | 92.06 | 85.71 | 56.31 |
YKL-40 or CEA | 74.00 | 83.20 | 84.09 | 72.73 |
YKL-40 or CYFRA21-1 | 82.00 | 77.78 | 81.46 | 78.40 |
CEA or CYFRA21-1 | 44.00 | 89.60 | 69.47 | 57.14 |
YKL-40 or CEA or CYFRA21-1 | 83.33 | 76.80 | 81.17 | 79.34 |