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Table 4 Multivariate analysis for local control (LC) and overall survival (OS)

From: Outcomes after stereotactic body radiotherapy for lung tumors, with emphasis on comparison of primary lung cancer and metastatic lung tumors

Variables

MVA for LC

MVA for OS

 

HR (95% CI)

P value

HR (95% CI)

P value

Gender (female vs. male)

n.s.

 

0.56 (0.34-0.88)

0.012*

Tumor origin (primary vs. metastatic lung tumors)

0.21 (0.09-0.47)

<0.001*

0.45 (0.28-0.73)

0.001*

Tumor diameter (per 1 cm increase)

1.70 (1.17-2.45)

0.005*

1.70 (1.30-2.21)

<0.001*

SUVmax (≥ 5.9 vs. < 5.9)

1.50 (0.66-3.61)

0.331

1.41 (0.81-2.48)

0.218

Prescription dose (BED10: > 105 Gy vs. ≤ 105 Gy)

0.51 (0.27-0.93)

0.029*

n.s

 

Date of treatment (2001–2005 vs. 2006–2011)

2.22 (1.19-4.23)

0.011*

n.s

 
  1. Abbreviations: MVA multivariate analysis, LC local control, OS overall survival, HR hazard ratio, CI confidence interval, SUVmax maximum standardized uptake value, BED10 biological effective dose calculated using α/β = 10; n.s. not significant. *p < 0.05.