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Table 3 Results of univariate and multivariate Cox regression analyses for overall survival (p < 0.05)

From: Bortezomib and dexamethasone for multiple myeloma: higher AST and LDH levels associated with a worse prognosis on overall survival

Features

Hazard

95% CI

p value

 

ratio

for hazard ratio

 

Univariate Cox regression

   

Age

1.09

1.01-1.17

0.027

Performance status

1.82

1.01-3.25

0.045

Stem cell transplantation

0.25

0.07-0.89

0.033

PLT

0.91

0.83-0.99

0.033

PDW

1.26

1.02-1.56

0.031

MPV

1.87

1.16-3.02

0.010

PLCR

1.08

1.02-1.15

0.013

K

2.15

1.09-4.27

0.028

AST

1.02

1.00-1.041

0.017

LDH

1.01

1.00-1.012

0.005

BUN

1.05

1.03-1.08

0.000

Creatinine

1.31

1.02-1.69

0.032

CRP

1.28

1.06-1.55

0.009

Multivariate Cox regression

   

AST

10.6

1.01-112

0.049

LDH

1.17

1.01-1.36

0.039

  1. 195% CI for hazard ration of AST is exactly 1.004-1.043.
  2. 295% CI for hazard ration of LDH is exactly 1.002-1.010.