Table 1 Clinicopathological variables in 92 consecutive pancreatoduodenectomies for pancreatic cancer stratified by COX-2 status
Characteristic | n(%) | COX2-neg. n(%) | COX2-pos. n(%) | pa |
|---|---|---|---|---|
COX-2 | ||||
Positive | 65 (71%) | |||
Negative | 27 (29%) | |||
Tumour size | ||||
≤ 20 mm | 15 (16%) | 3 (20%) | 12 (80%) | |
> 20 mm | 77 (84%) | 24 (31%) | 53 (69%) | 0.54b |
Lymph node metastasis | ||||
N0, n (%) | 25 (27%) | 5 (20%) | 20 (80%) | |
N1, n (%) | 67 (73%) | 22 (33%) | 45 (67%) | 0.229 |
Lymph node ratio (LNR)c | ||||
≤ 0.2 | 54 (59%) | 13 (24%) | 41 (76%) | |
> 0.2 | 37 (41%) | 13 (36%) | 24 (65%) | 0.251 |
Vascular invasion | ||||
No, n (%) | 30 (33%) | 12 (40%) | 18(60%) | |
Yes, n (%) | 62 (67%) | 15 (24%) | 47 (76%) | 0.119 |
Perineural infiltration | ||||
No, n (%) | 15 (16%) | 3 (20%) | 12 (80%) | |
Yes, n (%) | 77 (84%) | 24 (31%) | 53 (69%) | 0.54b |
T classification | ||||
T1 | 3 (3%) | 1 (33%) | 2 (67%) | |
T2 | 6 (7%) | 1 (17%) | 5 (83%) | |
T3 | 83 (90%) | 25 (30%) | 58 (70%) | 0.851b |
R1 resection status, n (%) | ||||
R0, n (%) | 40 (44%) | 10 (25%) | 30 (75%) | |
R1, n (%) | 52 (56%) | 17 (33%) | 35 (67%) | 0.422 |
Degree of differentiation | ||||
Grade I, II | 53 (58%) | 9 (17%) | 44 (83%) | |
Grade III, IV | 39 (42%) | 18 (46%) | 21 (54%) | 0.002 |
Type of differentiation | ||||
Pancreaticobiliary, n (%) | 84 (91%) | 27 (32%) | 57 (68%) | |
Intestinal, n (%) | 8 (9%) | 0 (0%) | 8 (100%) | 0.099b |