Figure 4
From: The genetic basis for inactivation of Wnt pathway in human osteosarcoma
Protein expression of the Wnt signaling pathway and its role in survival. A. WNT1 protein expression (IHC, 10 × 40). B. β-catenin protein expression (IHC, 10 × 40). C. c-myc protein expression (IHC, 10 × 40). D. Cyclin D1 protein expression (IHC, 10 × 40). E. Disease free time of WNT1-negative patients was not significantly longer than WNT1-positive patients. F. K-M survival analysis showed that patients negative for both WNT1 and cyclin D1 expression had significantly longer disease free survival time.