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Table 1 Summary of the multivariate longitudinal data analysis

From: Oncogenic MicroRNAs: miR-155, miR-19a, miR-181b, and miR-24 enable monitoring of early breast cancer in serum

A) miR-155
Parameter Estimate Standard error p -value
β I 0.61774 0.06440 < 2e-16
β II −0.24024 0.05617 1.89e-05
β III −0.34474 0.05684 1.32e-09
β C −0.51148 0.11103 4.10e-06
β L −0.18353 0.08245 0.026
B) miR-19a
Parameter Estimate Standard error p -value
β I 0.60941 0.04843 < 2e-16
β II 0.03224 0.03187 0.31183
β III 0.09981 0.03804 0.00869
β C 0.34506 0.11439 0.00256
β L 0.15711 0.07041 0.02567
C) miR-181b
Parameter Estimate Standard error p -value
β I 0.70370 0.05176 < 2e-16
β II 0.17814 0.03917 5.41e-06
β III 0.17263 0.03884 8.80e-06
β C 0.27792 0.10095 0.0059
β L 0.16588 0.07403 0.0250
D) miR-24
Parameter Estimate Standard error p -value
β I 0.50276 0.06718 7.19e-14
β II −0.14807 0.05429 0.00638
β III −0.12527 0.05527 0.02343
β C −0.34034 0.11512 0.00311
β L −0.22631 0.08774 0.00990
  1. Presented are parameters to calculate conditional expectation of the miR’s serum level for each BC patient/control at particular time point and their estimate values, their standard errors, and corresponding p-values for levels of miR-155 (A), miR-19a (B), miR-181b (C), and miR-24 (D), all relative to let-7a, in EBC sera. Parameters of oncomiR level: β I : time point I, β II : the difference between time points I and II, β III : the difference between time points I and III, β C : the difference between time point I and healthy control, and β L : the difference between high risk and low risk EBC patients.